You have full access to this open access article. Results from their MBSQs and from well-established patient-reported outcome measures indicated severe impairments of daily activities and health-related quality of life. While many patients recover from PASC within few months, some endure a long lasting disorder, affecting social participation and health-related quality of life HRQoL [ 4 , 8 , 9 , 10 ].
Estimating pediatric PCC prevalence is challenging [ 8 , 14 ], with 0. These symptoms can persist, fluctuate, or relapse and may have a significant impact on everyday functioning [ 11 , 12 , 18 , 19 , 20 ]. Rowe and colleagues CDW-R [ 48 ]. A symptom duration of at least 6 months is usually required for adult patients [ 31 ], but was suggested to be reduced cross-age to facilitate early treatment [ 49 ].
Adequate care can lead to substantial improvement, particularly in young patients, often recovering within a decade [ 32 ]. To increase diagnostic sensitivity, the frequency and severity of symptoms should be assessed [ 54 , 55 ]. Written informed consent was obtained from all participants or parents prior to inclusion. The SF consists of eight dimensions, including physical functioning, social functioning, vitality, general health, mental health, role physical, role emotional, and bodily pain.
The score of each dimension is scaled to 0β, with 0 representing the worst and the best health status. Analyses varied based on symptoms, with core routine tests following prior recommendations [ 48 ].
Routine technical investigations included pulmonary function testing PFT , electrocardiography, and ultrasound cardiography. Alternatively, psychological evaluation was performed externally and reports discussed internally. Home pre-filling saved time and let physicians focus on clarifications. For developing the MBSQs, all terms used to describe the symptoms in the original publications [ 45 , 46 , 47 , 48 ] were mapped to the eight CCC symptom categories fatigue, PEM, sleep disorder, pain, neurocognitive, autonomic, neuroendocrine, and immunologic manifestations.
