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Medpedia Podcast. Apps Newsletter Abo-Shop. Springer Medizin. Suche Suchbegriffe eingeben Suchen. Abstract Hypercholesterolemia is a major risk factor in the development of cardiovascular diseases. Statins have been the primary treatment for reducing LDL cholesterol for years; however, adverse events related to their use have led to the development of alternative therapies, such as ezetimibe, bempedoic acid, and PCSK9 inhibitors, including alirocumab, evolocumab, and inclisiran.
The study is aimed at comparing the consumption and costs of lipid-lowering drugs in the first half of 21,, Dispensing data, without access to patient data, were collected from private community pharmacies and hospital and district pharmacies. The study revealed a trend toward a reduction in the use of traditional statin monotherapy and an increase in more recent and combined therapies.
In recent years, the treatment of dyslipidemia has seen the introduction of many therapeutic alternatives. Bempedoic acid, recently introduced and less expensive, when used as an adjunct therapy with statins and ezetimibe, could reduce side effects and improve therapeutic efficacy without immediately resorting to higher-cost injectable drugs such as evolocumab, alirocumab, and inclisiran.
Monitoring prescription trends and costs is essential to maintain the sustainability of the healthcare system, enabling investments in innovation and effective therapies without waste. Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten.
Jetzt einloggen Kostenlos registrieren. Atherosclerosis β Prog Cardiovasc Dis β JAMA Cardiol 5 10 β Expert Opin Drug Saf 21 1 :9β Eur Heart J 44 38 β Erratum in: Eur Heart J. Eur Heart J 43 34 β Eur J Health Econ 25 1 :1β5. JAMA 19 β Am J Cardiol 15 β Indian J Pharmacol 52 5 β Int J Clin Pharm 43 5 β Curr Probl Cardiol 48 10 Curr Probl Cardiol 48 5 Eur J Pharmacol 5 Lancet β Eur Heart J 44 11 β J Am Coll Cardiol 81 14 β Am J Cardiovasc Drugs 16 6 β Curr Cardiol Rep 22 8 Front Cardiovasc Med 25 11 N Engl J Med 15 β JAMA 2 β Curr Atheroscler Rep 25 3 β Front Cardiovasc Med 22 9 N Engl J Med 11 β Lancet Reg Health Eur Eur Heart J 43 8 β Eur Heart J 42 3 β Can J Cardiol 37 5 β Int J Mol Sci 22 21 Eur Heart J 42 34 β Cardiovasc Drugs Ther 37 2 β Redox Biol Titel Considerations on the sustainability of hypercholesterolemia treatment in the context of new drugs on the market: data from Campania, Italy.