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Official websites use. Share sensitive information only on official, secure websites. This article was submitted to Cancer Molecular Targets and Therapeutics, a section of the journal Frontiers in Oncology. The use, distribution or reproduction in other forums is permitted, provided the original author s and the copyright owner s are credited and that the original publication in this journal is cited, in accordance with accepted academic practice.
No use, distribution or reproduction is permitted which does not comply with these terms. Data relating to research design, sample population, type of electro-cosmetic devices used, were extracted. Our research is in favor of moderate periodical use of cosmetic medical devices in patients bearing tumors, in any stage, like in healthy people. Special consideration is dedicated to massage, manipulation, and pressure delivery upon the cytoskeleton of cancer cells that has proven to be sensitive to mechanical stress at least in some specific locally relapsing cancers such as osteosarcoma.
Keywords: cancer, esthetics, oncology esthetics, medical devices, cosmetic, electro-cosmetic device, onco-esthetic, esthetician. Genetic and epigenetic events define the evolution from normal cells to the malignant state, up to death.
Tumor progression is determined by molecular mechanisms, almost completely identified, acting progressively step by step until the end of the life. In , Hanahan and Weinberg developed the first 6 hallmarks of cancer that became 10 in 1. Uncontrolled proliferation: healthy cells actively control the growth cycle and cell division ensuring homeostasis and maintenance of tissue architecture and function. Cancer cells counteract these signals resulting in uncontrolled cell growth 1.
Altered metabolism: the cancer cell metabolism is mainly based on aerobic glycolysis that breaks down glucose in aerobic conditions 1. Replicative immortality: normal cellular aging is consistent with shortening of telomeres; cancer cells do not reduce their length. Block of the onco-suppressor genes: onco-suppressors have been discovered by experimental activation—inactivation in mice or human cancer tissues.