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Official websites use. Share sensitive information only on official, secure websites. Author contributions: Han XM and Cen LS contributed to manuscript writing and editing, and data collection; Zhou YM contributed to data analysis; Cen LS contributed to conceptualization and supervision; and all authors have read and approved the final manuscript. This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers.
In addition to the non-specific symptomatology of ocular rosacea, currently, there are no reliable diagnostic tests for the disease, which may lead to its misdiagnosis.
Here, we report a case of ocular rosacea presenting with multiple recurrent chalazion on both eyelids. A year-old female patient presented with multiple chalazion and dry eyes in both eyes, with no facial erythema. Initial management done were application of steroid eye ointment on both eyelids, hot compresses, and eyelid margin cleaning; noting that there was no relief of symptoms. Surgical excision of the chalazion was done on both eyes, however, bilateral recurrence occurred post-operatively.
The pathological studies showed infiltration of a small amount of fibrous tissue with many chronic inflammatory cells. Immunohistochemistry studies were positive for LL Resolution of the chalazion occurred after oral administration of doxycycline and azithromycin.
Our findings show that ophthalmologists should recognize the ocular manifestations of skin diseases. Core Tip: In this study, we demonstrate for the first time that bilateral recurrent chalazion refractory to conventional treatment may indicate ocular rosacea.