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The day will showcase a wide range of cutting-edge research on clinical applications of brain technologies from within and beyond the BRC, with sessions on brain stimulation, imaging and neurophysiology. Please register by January 27th. Retroviruses, such as human immunodeficiency virus 1 HIV-1 , contain capsids that enclose the viral RNA genome, enzymes, and accessory proteins. The assembly, maturation, and stability of the viral capsid are critical to the viral replication life cycle.
Furthermore, the surface of the viral capsid serves as a primary interaction interface between the virus and the host cell, for both host defense proteins and virus dependence factors. I will describe HIV-1 capsid assembly and interactions with host factor IP6 and cyclophilin A, highlighting unexpected novel interactions that are critical for these host factors to stabilize the HIV-1 capsid. I will present our recent in situ studies of nuclear import of intact HIV-1 capsid and the architecture of native chromatin fibers in T-cells.
The Census of England and Wales was the first to count the transgender population. When the results were released, I immediately realised that they were not plausible. This talk will summarise my statistical analysis which demonstrated the errors and my explanation for why the Office for National Statistics adopted such a confusing question. The broader lesson is that statistical data always deserve critical scrutiny.
Please join either in person or online. For in-person attendees, the talk will be preceded by a light lunch at Please email comms sociology. Difficulties in one area of childhood functioning can influence others. But the interplay between different areas of functioning e. Next, latent class models were fitted to the same data to determine whether there are sub-groups of children who share similar profiles of difficulties.
The findings from these analyses will be discussed as well as potential implications for how children with special educational needs are supported. However, RNA vaccination is still a young platform and the success of RNA vaccines has outstripped understanding of how they work.